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NAPPA Protein Array Core
The NAPPA Protein Array Core uses a novel protein microarray technology, called Nucleic Acid-Programmable Protein Array (NAPPA), which replaces the complex process of spotting purified proteins with the simple process of spotting plasmid DNA. Our facility offers high throughput DNA preparation, pre-set and custom protein array production, and array screening and analysis services. For move information, please contact the Core Manager.NEWS AND ANNOUNCEMENTS
February 2017:
Paper published in Molecular & Cellular Proteomics: Identification of Antibody Targets for Tuberculosis Serology using High-Density Nucleic Acid Programmable Protein Arrays.January 2014:
We will be presenting a poster at the 2014 SLAS Conference about our High Throughput DNA preparation services. Visit our poster 258 on Monday January 20th.
September 2013:
The NAPPA Protein Array Core formed a new collaboration with Emory University.
July 2013:
Presented at the HighRes Biosolutions user group meeting in Boston, MA.
April 2013:
Proteins are expressed using a new system extracted from human HeLa cells (1-Step Human Coupled in vitro translation) from Thermo Scientific. Take a look at our publication describing our use of this lysate to display protein on the NAPPA arrays.
March 2013:
In collaboration with HighRes Biosolutions, we have installed a robotic DNA preparation system called the DNA Factory. This unique system allows us to prep 4,800 plasmids in 72 hours with limited technician intervention. Within the next few months, high throughput DNA preparation services will be available to the research community.
